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M94A3120.TXT
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1994-10-25
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Document 3120
DOCN M94A3120
TI Trace elements in patients with HIV-1 infection.
DT 9412
AU Peraire J; Vidal F; Schuhmacher M; Domingo J; Porras J; Richart C;
Department of Internal Medicine, Hospital Joan XXIII, Tarragona,; Spain.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):149 (abstract no. PB0022). Unique
Identifier : AIDSLINE ICA10/94369455
AB OBJECTIVE: To provide a detailed characterization of trace elements
concentrations in patients with HIV-1 infection. METHODS: Serum and
urinary zinc, selenium, copper, iron, magnesium and manganese
concentrations were determined in 19 patients AIDS (IVC1, CDC 1987)
compared to 25 individuals with asymptomatic infection (II, CDC 1987)
and 18 healthy controls. RESULTS: Serum concentrations are reported in
the table. There was a significant decrease in the serum selenium levels
in both groups of HIV infected patients vs controls. No significant
differences between groups were found in the urinary levels of the trace
elements. TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSIONS:
Patients infected by HIV-1 have marked selenium deficiency. Since some
have reported that a low level of selenium may have a direct effect on
T-cell dependent immune function, further studies are justified to
evaluate the effect of selenium supplements over immune status of HIV-1
infected patients.
DE Acquired Immunodeficiency Syndrome/*BLOOD/URINE Analysis of Variance
Comparative Study Copper/BLOOD Human HIV Seropositivity/*BLOOD/URINE
*HIV-1 Iron/BLOOD Magnesium/BLOOD Manganese/BLOOD Reference Values
Selenium/BLOOD Trace Elements/*BLOOD/URINE Zinc/BLOOD MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).